Inj. Ligno – Ad, Ligno ?Ad is a lignocaine based anaesthetic in sterile injectable form. Lignocaine stabilizes the neuronal membrane and prevents the initiation and conduction of nerve impulses, thereby effecting local anaesthetic. Lignocaine is metabolized mainly in liver and excreted via the kidneys. Approximately 90% of lignocaine administered is excreted in the form of various metabolites, while less than 10% is excreted unchanged. The presence of adrenalin, a vasoconstrictor, in the formulation prolongs the action of the anaesthetic localizing later to the site of injection. Therefore, the rate at which the anarsthetic passes into the bloodstream is reduced. In addition, the vasoconstrictor reduces haemorrhaging during surgical procedures in the vicinity of the injection, thus, facilitating clinical care.
Inj. Ligno – Ad, Ligno ?Ad is a lignocaine based anaesthetic in sterile injectable form. Lignocaine stabilizes the neuronal membrane and prevents the initiation and conduction of nerve impulses, thereby effecting local anaesthetic. Lignocaine is metabolized mainly in liver and excreted via the kidneys.
Approximately 90% of lignocaine administered is excreted in the form of various metabolites, while less than 10% is excreted unchanged. The presence of adrenalin, a vasoconstrictor, in the formulation prolongs the action of the anaesthetic localizing later to the site of injection.
Therefore, the rate at which the anarsthetic passes into the bloodstream is reduced. In addition, the vasoconstrictor reduces haemorrhaging during surgical procedures in the vicinity of the injection, thus, facilitating clinical care. Composition: Each ml contains:
Lignocaine Hydrochloride I.P. 21.3 mg Adrenaline Bitrate I.P. 0.005 mg (as Adrenaline bitrate IP o.oo9mg.) Adrenaline 0.0125 mg Methyl Paraben I.P. 1.0 mg (As preservative) Water for injection I.P. Q.S.
Indication: Ligno-Ad is indicated for the production of local anaesthesia for dental procedures by infiltration or nerve block injections. Contra-indication Ligno-Ad is contra ?indicated in patients with a known history of hypersensitivity to local anaesthetics of the amide type or to any components of the injectable formulation.
Ligno-Ad, due to the presence of a vasoconstrictor (Adrenaline) in the formula, is contra-indicated for patients suffering from: ? Arterial hypertension ? Coronary disease Valvular cardiac disease (particularly sequelae to acute rhematic fever).
Product Benefit: 1. Simple, Smooth and effective Anaesthetic 2. Extraction of tooth and Oral Surgery 3. Fast and effective.
How to use: Adults: 2 ml. is generally sufficient. 4ml. may be used in the case of large interventions. However, 4 to 6ml. may be used if deemed necessary for procedures. Adolescents between 14 to 17 and the Elderly: Usual dose 1.8 ml Do not exceed 3.75ml. Children between 6 and 14: Usual dose 1 to 1.5 ml. Do not exceed 2.5 ml. Children between 3o and 6: Usual dose 1 to 1.5ml Do not use under 3 years of age. Packing: 1 X 30ml. Vial.
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